A Guide to the Ronavax — Understanding the Experimental Coronavirus Vaccines
Around 150 vaccines are being developed for the alleged* rona virus, but the ones that deserve the most attention are the ones winning contracts and/or being trialled already, because their success is almost guaranteed. Some people want them, some never think about it, and others worry they could be coerced or physically forced to get them. The thing is, everyone should have access to information so they can make informed choices about what is right.
Two of these ronavax are vaguely similar to the kind of vaccines that have been licensed in the past. One is made by Sanofi/GSK – selected for Operation Warp Speed in the U.S., this vaccine contains proteins that are made in a bioreactor, using genetically engineered baculoviruses and insect cells. This is a method of protein engineering. Novavax, also funded by the US government uses a similar technique, but packages the proteins in nanoparticles. The idea behind these vax is the same as ‘normal’ vaccines, because the proteins are designed to look like the ones the rona is said to make (usually referred to as the spike or ‘S’ protein) so that your body reacts to them as if they were ‘the real thing’.
This is done by smuggling genetic instructions into your cells, using one of three methods:
- Adenoviruses which have been genetically modified to contain or ‘express’ the gene of interest (used by AstraZeneca and J&J/Janssen)
- Lipid nanoparticles with mRNA (used by Pfizer/BioNTech, Curevac, and Moderna)
- DNA plasmids (used by INOVIO, a company worth noting because of its novel techniques, strategic partnerships and product pipeline)
They are all ‘delivery vehicles’ or ‘vectors’ – a way to get the DNA/mRNA into your cells.
They are all methods used in gene therapy. If the ronavax are licensed, not only could gene therapy become very big business, but restrictions on genetic patents could be loosened. Most current gene therapy products are for very specific conditions, e.g. LUXTURNA which uses the RPE65 gene for patients with an inherited retinal disease. However, because genvax use the same techniques, getting the ronavax to market could begin a new era of busy production lines in bio-factories, meaning they could also churn out some of the other ‘therapeutics’ that have been planned.
DNA and mRNA are said to be ‘the software of life’ and the possibilities are endless. So, perhaps, are the dangers. Because, whilst the platform or vector remain the same, the software doesn’t. For each new application, or disease, a new genetic code is designed on computers. Then, the new
Article from LewRockwell