Death Clock Discovered. Clock-Hands of Biological Time Can Be Reversed With Red Wine Molecule
105-Year-Old Man In Italy Discovered With An Immune System Of A 25-Year Old
CXCL9 Protein In Blood Determines “How Far Along A Person Is In Their Inexorable March To The Grave.”
Red Wine Molecule May Produce Biologically Young Centenarians
Researchers at Stanford University and the Buck Institute announce the remarkable discovery of a biological clock in human blood that can determine your “inflammatory age” (iAge) which equates with longevity. iAge can now be used to track risk to develop chronic age-related frailty. Anticipate blood test kits to be available soon.
The team of investigators identified CXCL9, an inflammatory protein that biologists call chemokines, as the strongest contributor to iAge. CXCL9 is called into action when white blood cells are required to respond to infection.
Epigenetic “silencing” of CXCL9 reverses chronic inflammation. In fact, aging has been redefined as “inflammaging.” Gene silencing is when gene protein-making is halted. The term “inflammaging” was first coined in 2000 as the hallmark sign of aging.
CXCL9 not only activates genes involved in inflammation but also induces cellular senescence, blood vessel aging, and adverse changes in the size, mass and function of the heart. Cellular senescence is when living cells cease division and renewal.
CXCL9 Protein Determines “How Far Along A Person Is
In Their Inexorable March To The Grave.”
Researchers say the CXCL9 protein helps determine “how far along a person is in their inexorable march to the grave.”
The age of your immune system can now be measured
On average, centenarians have an immune system that is 40 years younger than what is considered normal. “We have an outlier, a super-healthy 105-year old man who lives in Italy who has the immune system of a 25-year old,” said researchers.
Researchers in the field of aging now say they need to pay more attention to the immune system with advancing age, given that almost every malady of aging involves inflammation.
The discovery was made after blood analysis of 1,001 individuals and is published in the journal NATURE AGING.
CXCL Family Of Inflammatory Proteins
CXCL9 was first described as part of a family of “chemokines” in the 1990s. CXCL9 and its family of inflammatory proteins activate lymphocytes, white blood cells such as natural killer cells, T-cells (thymus cells), and B-cells (bone marrow cells) that are ma
Article from LewRockwell